![The Vibrio cholerae MARTX toxin silences the inflammatory response to cytoskeletal damage before inducing actin cytoskeleton collapse The Vibrio cholerae MARTX toxin silences the inflammatory response to cytoskeletal damage before inducing actin cytoskeleton collapse](https://www.science.org/cms/10.1126/scisignal.aaw9447/asset/feab3cf7-c104-45e0-8ab5-98b67a2e8a1e/assets/graphic/aaw9447-f1.jpeg)
The Vibrio cholerae MARTX toxin silences the inflammatory response to cytoskeletal damage before inducing actin cytoskeleton collapse
![Bacterial RTX Toxins Allow Acute ATP Release from Human Erythrocytes Directly through the Toxin Pore* - Journal of Biological Chemistry Bacterial RTX Toxins Allow Acute ATP Release from Human Erythrocytes Directly through the Toxin Pore* - Journal of Biological Chemistry](https://els-jbs-prod-cdn.jbs.elsevierhealth.com/cms/attachment/ce70b7d1-8c26-41a1-80d5-110c46608484/gr1_lrg.jpg)
Bacterial RTX Toxins Allow Acute ATP Release from Human Erythrocytes Directly through the Toxin Pore* - Journal of Biological Chemistry
![The Bordetella Adenylate Cyclase Repeat-in-Toxin (RTX) Domain Is Immunodominant and Elicits Neutralizing Antibodies* - Journal of Biological Chemistry The Bordetella Adenylate Cyclase Repeat-in-Toxin (RTX) Domain Is Immunodominant and Elicits Neutralizing Antibodies* - Journal of Biological Chemistry](https://els-jbs-prod-cdn.jbs.elsevierhealth.com/cms/asset/7520f628-e946-495a-b9ab-e6fcf9cb1a78/gr1.jpg)
The Bordetella Adenylate Cyclase Repeat-in-Toxin (RTX) Domain Is Immunodominant and Elicits Neutralizing Antibodies* - Journal of Biological Chemistry
![Channel formation by RTX-toxins of pathogenic bacteria: Basis of their biological activity - ScienceDirect Channel formation by RTX-toxins of pathogenic bacteria: Basis of their biological activity - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S000527361500365X-gr1.jpg)
Channel formation by RTX-toxins of pathogenic bacteria: Basis of their biological activity - ScienceDirect
![RCSB PDB - 5CXL: CRYSTAL STRUCTURE OF RTX DOMAIN BLOCK V OF ADENYLATE CYCLASE TOXIN FROM BORDETELLA PERTUSSIS RCSB PDB - 5CXL: CRYSTAL STRUCTURE OF RTX DOMAIN BLOCK V OF ADENYLATE CYCLASE TOXIN FROM BORDETELLA PERTUSSIS](https://cdn.rcsb.org/images/structures/cx/5cxl/5cxl_assembly-1.jpeg)
RCSB PDB - 5CXL: CRYSTAL STRUCTURE OF RTX DOMAIN BLOCK V OF ADENYLATE CYCLASE TOXIN FROM BORDETELLA PERTUSSIS
![The Actin Cross-linking Domain of the Vibrio cholerae RTX Toxin Directly Catalyzes the Covalent Cross-linking of Actin* - Journal of Biological Chemistry The Actin Cross-linking Domain of the Vibrio cholerae RTX Toxin Directly Catalyzes the Covalent Cross-linking of Actin* - Journal of Biological Chemistry](https://els-jbs-prod-cdn.jbs.elsevierhealth.com/cms/asset/44e3a985-645a-4c36-8879-3175ea496695/gr1.jpg)
The Actin Cross-linking Domain of the Vibrio cholerae RTX Toxin Directly Catalyzes the Covalent Cross-linking of Actin* - Journal of Biological Chemistry
![Toxins | Free Full-Text | Membrane Permeabilization by Pore-Forming RTX Toxins: What Kind of Lesions Do These Toxins Form? | HTML Toxins | Free Full-Text | Membrane Permeabilization by Pore-Forming RTX Toxins: What Kind of Lesions Do These Toxins Form? | HTML](https://www.mdpi.com/toxins/toxins-11-00354/article_deploy/html/images/toxins-11-00354-g003.png)
Toxins | Free Full-Text | Membrane Permeabilization by Pore-Forming RTX Toxins: What Kind of Lesions Do These Toxins Form? | HTML
![Identification of a Vibrio cholerae RTX toxin gene cluster that is tightly linked to the cholera toxin prophage | PNAS Identification of a Vibrio cholerae RTX toxin gene cluster that is tightly linked to the cholera toxin prophage | PNAS](https://www.pnas.org/cms/10.1073/pnas.96.3.1071/asset/d58c340e-3caa-4c3e-a134-b8d85bfb4c3c/assets/graphic/pq0394623001.jpeg)
Identification of a Vibrio cholerae RTX toxin gene cluster that is tightly linked to the cholera toxin prophage | PNAS
![Coordinated delivery and function of bacterial MARTX toxin effectors - Woida - 2018 - Molecular Microbiology - Wiley Online Library Coordinated delivery and function of bacterial MARTX toxin effectors - Woida - 2018 - Molecular Microbiology - Wiley Online Library](https://onlinelibrary.wiley.com/cms/asset/089de67e-060c-479b-afa7-ad0a8eba37d2/mmi13875-fig-0003-m.jpg)
Coordinated delivery and function of bacterial MARTX toxin effectors - Woida - 2018 - Molecular Microbiology - Wiley Online Library
PLOS ONE: Membrane localization of the Repeats-in-Toxin (RTX) Leukotoxin (LtxA) produced by Aggregatibacter actinomycetemcomitans
![Vibrio cholerae Strains with Mutations in an Atypical Type I Secretion System Accumulate RTX Toxin Intracellularly | Journal of Bacteriology Vibrio cholerae Strains with Mutations in an Atypical Type I Secretion System Accumulate RTX Toxin Intracellularly | Journal of Bacteriology](https://journals.asm.org/cms/10.1128/JB.186.23.8137-8143.2004/asset/1e1ae25b-b2ed-430b-af3a-490c046cb4f2/assets/graphic/zjb0230442370005.jpeg)
Vibrio cholerae Strains with Mutations in an Atypical Type I Secretion System Accumulate RTX Toxin Intracellularly | Journal of Bacteriology
![Identification of a domain within the multifunctional Vibrio cholerae RTX toxin that covalently cross-links actin | PNAS Identification of a domain within the multifunctional Vibrio cholerae RTX toxin that covalently cross-links actin | PNAS](https://www.pnas.org/content/101/26/9798/F1.large.jpg)
Identification of a domain within the multifunctional Vibrio cholerae RTX toxin that covalently cross-links actin | PNAS
![Different roles of conserved tyrosine residues of the acylated domains in folding and activity of RTX toxins | Scientific Reports Different roles of conserved tyrosine residues of the acylated domains in folding and activity of RTX toxins | Scientific Reports](https://media.springernature.com/lw685/springer-static/image/art%3A10.1038%2Fs41598-021-99112-3/MediaObjects/41598_2021_99112_Fig3_HTML.png)
Different roles of conserved tyrosine residues of the acylated domains in folding and activity of RTX toxins | Scientific Reports
PLOS ONE: Membrane localization of the Repeats-in-Toxin (RTX) Leukotoxin (LtxA) produced by Aggregatibacter actinomycetemcomitans
![Toxins | Free Full-Text | Structure–Function Relationships of the Repeat Domains of RTX Toxins | HTML Toxins | Free Full-Text | Structure–Function Relationships of the Repeat Domains of RTX Toxins | HTML](https://www.mdpi.com/toxins/toxins-11-00657/article_deploy/html/images/toxins-11-00657-g003.png)
Toxins | Free Full-Text | Structure–Function Relationships of the Repeat Domains of RTX Toxins | HTML
![RCSB PDB - 6SUS: Crystal structure of RTX domain blocks IV and V of adenylate cyclase toxin from Bordetella pertussis RCSB PDB - 6SUS: Crystal structure of RTX domain blocks IV and V of adenylate cyclase toxin from Bordetella pertussis](https://cdn.rcsb.org/images/structures/su/6sus/6sus_assembly-1.jpeg)